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Compound extracted from tree 'can help fight leukemia'

Kuala Lumpur, Dec 14 (ANI): A new compound is showing promise against some forms of cancer like leukemia.

The compound comes from the Aglaia foveolata tree, found in Sarawak's highlands, and has entered pre-clinical trials.

Scientists at the Sarawak Biodiversity Centre (SBC), which owns the intellectual property rights to the plant, say that the experiments found an extracted compound called Silvestrol offered benefits not found in other cancer-fighting drugs.

"First, it seems to inhibit leukaemia growth compared with controlled tests performed on mice. Second, the tests show that it seems to bypass drug resistance," the Star Online quoted Dr Yeo Tiong Chia, senior research officer at the center, as saying.

Dr Yeo, a graduate of the Washington University in immunology, said he was confident of the compound's potential. (ANI)

Scientists uncover compound that frees trapped cholesterol

Washington, January 27 (ANI): Scientists at UT Southwestern Medical Center have identified a compound that can free cholesterol that has inappropriately accumulated to excessive levels inside cells.The researchers say that their discovery in mice shed light on how cholesterol is transported through the cells of the body, and suggest a possible therapeutic target for Niemann-Pick type C disease (NP-C), an inherited neurodegenerative disorder characterized by abnormally high cholesterol levels in every organ."What we've shown is that very quickly.....
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