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The Hobbit's small brain was not unusual in comparison to other primates

Washington, January 27 (ANI): In a new study, scientists have found out that the reduction in brain size during the evolution of the ancient hominid species known as 'the hobbit', is not unusual in comparison to other primates.

Homo floresiensis, a pygmy-sized small-brained hominin popularly known as 'the Hobbit' was discovered five years ago, but controversy continues over whether the small brain is actually due to a pathological condition.

Now, a research team has tackled this question in the context of a comprehensive assessment of the evolution of brain and body size throughout the larger primate family.

Nick Mundy and Stephen Montgomery, from the Department of Zoology at Cambridge University, UK, and colleagues from Durham University used previously published data from living and extinct species to reconstruct the pattern of brain and body mass evolution in primates.

According to Nick Mundy, "Our results provide robust confirmation for the suggestion that strong evolutionary trends have governed the expansion of the primate brain."

"In contrast, body size evolution has not tended to increase in primates, implying brain and body mass have been subject to separate selection pressures and supporting the findings of previous studies in other taxonomic groups that these two highly correlated traits can show differences in their patterns of evolution," he said.

Brain expansion began early in primate evolution and has occurred in all major groups, suggesting a strong selective advantage to increased brainpower in most primate lineages.

Despite this overall trend, however, Mundy and his colleagues have identified several branches/lineages within each major group that have shown decreasing brain and body mass as they evolve, for example in marmosets and mouse lemurs.

"We find that, under reasonable assumptions, the reduction in brain size during the evolution of Homo floresiensis is not unusual in comparison to these other primates," said Mundy.

"Along with other recent studies on the effects of 'island dwarfism' in other mammals, these results support the hypothesis that the small brain of Homo floresiensis was adapted to local ecological conditions on Flores," he added. (ANI)

Small molecule drug may help treat hormone-accelerated breast cancer

Washington, January 29 (ANI): University of Missouri scientists in the United States say that a small molecule drug has the potential as a novel chemotherapeutic treatment for breast cancer accelerated by the hormone progestin.The researchers have revealed that the drug called PRIMA-1 targets the most common mutated gene, p53, in human cancer cells."We demonstrated that PRIMA-1 was an effective drug to treat and prevent emergence of progestin-accelerated mammary tumors in rats," said Salman Hyder, professor of biomedical sciences.....
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