London, Feb 21 : Actress Angelina Jolie suffered a major health shock in mid-air and collapsed during an 18-hour flight.

The 'Tomb Raider' star, who is said to pregnant with twins, was on her way to Los Angeles from Iraq when she suffered from nosebleeds and cramps and fainted on her plane seat.

"She started to get nosebleeds and cramps. She fainted," The Sun quoted a fellow passenger, as saying.

The actress was reportedly given oxygen when she landed before medics gave her the go-ahead to leave.

Meanwhile Jolie and partner Brad Pitt, who have three adopted kids and one of their own, have reportedly agreed a 100-million-pound pre-nup contract prior to their wedding.

ANI